Why a 20mg/ml GS-441524 formulation?

Aktualizacja: 8 wrz 2020

Reason #1: RELAPSE!

That dreaded event when a cat seemingly fought and won against FIP virus, only to fall victim to it several weeks or months later. Relapse happens to all brands. Some of relapse cases are caused by poor quality of the GS used. Others are due to improper dosage. And of course, there are genetic and environmental factors which we can't control.

Relapse certainly has happened to cats using our brand. After treating 1000 cats, we have calculated the percentage of cats fallen victim to relapse using our brand to 2.6%. (Read about how we treated 1000 cats with FIP and what we have learned.)

But more often cat owners contact us after their cats have relapsed after completing treatment using another brand. Usually they have lost faith in their former brand, or they simply want to try another brand hoping to avoid another relapse. Of the relapse cases that have came to us for help, a large number of them used Oral GS-441524 during initial treatment. (Read our blog about oral GS-441524)

Reason #2: Larger Cats

Even after treating 1000+ cats, we are still amazed at the size and weight of modern cats that have grown up eating formulated diets. It is not rare to receive photos and videos of 5, 6, even 7kg cats. For larger cats, injections using 15mg/ml can be difficult and painful.

Example: A 5kg cat with Neurological FIP

Using 15mg/ml, one injection requires 3.33ml

Using 20mg/ml, one injection requires 2.50ml

As you can see from the calculation above, using a 20mg/ml formulation will save you and your cat 0.83ml per injection. For those who are not familiar with subcutaneous injections, 0.83ml is a lot of fluid to inject.

Reason #3: Neurological FIP Cases

For cats suffering from neurological symptoms the window for treatment is closing fast. The amount of FIP virus and its progression inside a cat's the body is reaching the tipping point of biological shutdown. Cats with neurological symptoms need large amount of GS-441524 to arrest further replications of the FIP virus. Only then can we bring these cats back from the brinks of death and begin the healing process. Cats with neurological symptoms on average require the lengthiest treatment and the greatest dosage. For neurological cases, we strongly recommend give two 20mg/ml injections per day, 12 hours apart; each injection using 50% of the daily recommended dosage. From our experiments, this is the most secure way of delivering sufficient amount of GS-441524 to a cat's bloodstream to combat FIP virus.

We greatly hope that our new 20mg/ml formulation will increase the success rate of FIP treatment, allow cat owners and doctors to have an easier time administering GS-441524.

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Published by: curefip.com

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